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BooksThe Gene: An Intimate History
Cover of The Gene: An Intimate History by Siddhartha Mukherjee

The Gene: An Intimate History,

by Siddhartha Mukherjee

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Rating4.3/ 5
Ratings96
Pages560
Reading Hours12h
Published2016
Language—

§Synopsis

01

Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a ‘unit of heredity’. It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. Above all, this is a story driven by human ingenuity and obsessive minds–from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes. This is an epic, moving history of a scientific idea being brought to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history–the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to ‘read’ and ‘write’ the human genome–unleashing the potential to change the fates and identities of our children. Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity–and a vision of both humanity’s past and future.

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§About the Author

Siddhartha Mukherjee
Siddhartha Mukherjee

3 books in catalog

Illuminating the complex histories of human cellular biology, genetics, and oncology, popular science literature gained profound depth through The Emperor of All Maladies: A Biography of Cancer. Siddhartha Mukherjee, an oncologist and medical researcher, brought both clinical precision and literary narrative to the study of disease, transforming dense biomedical concepts into accessible accounts for general readers.

Career & Background

Born in New Delhi, India, in 1970, Mukherjee earned a Bachelor of Science in biology from Stanford University before attending the University of Oxford as a Rhodes Scholar, where he earned a DPhil in immunology. He went on to receive his MD from Harvard Medical School and completed his internal medicine residency and oncology fellowship at Massachusetts General Hospital. As a practicing hematologist, oncologist, and researcher, he serves as an assistant professor of medicine at Columbia University Medical Center in Manhattan, where he lives with his wife, artist Sarah Sze, and their two daughters. Beyond his book-length non-fiction, his scientific and medical writing has appeared in prominent journals and publications such as Nature, The New England Journal of Medicine, Cell, and The New York Times.

Writing Style & Themes

Mukherjee's work bridges clinical case studies, historical archival research, and personal reflections from his practice as a physician. By combining rigorous biological history with human stories of patients, researchers, and clinicians, his writing examines how cellular processes and genetic discoveries shape human identity, treatment paradigms, and medical ethics. He frequently incorporates firsthand observations from his laboratory and hospital rounds, rejecting detached detachment in favor of an engaged perspective that contextualizes fundamental scientific breakthroughs within human experience.

Major Works

  • The Emperor of All Maladies: A Biography of Cancer — Published in 2010, this history of cancer research and treatment won the 2011 Pulitzer Prize for General Nonfiction and the Guardian First Book Award. It was listed among Time magazine's 100 most influential nonfiction books in 2011 and served as the basis for a television documentary film.
  • The Gene: An Intimate History — This #1 New York Times bestseller explores the history and science of genetics from Gregor Mendel to contemporary gene editing, interweaving scientific history with Mukherjee's own family medical history. The book was a finalist for the Wellcome Trust Prize and the Royal Society Prize for Science Books.
  • The Song of the Cell: An Exploration of Medicine and the New Human — Focusing on cellular biology and the evolution of cell therapy, this book examines how the discovery of the cell reshaped human understanding of physiology, pathology, and novel therapeutic interventions.
  • Best Science Writing 2013 — Mukherjee served as the editor for this 2013 anthology, curating an array of outstanding science journalism and essays.

§Editions

Cover of The Gene: An Intimate History

The Gene: An Intimate History

592 pgs
20169781476733500

Metadata

ISBN-139781476733500
ISBN-101476733503

Editions and availability

Find The Gene: An Intimate History Siddhartha Mukherjee in PDF, EPUB, ebook, audiobook, print, or library editions.

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